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Clonal competition within complex evolutionary hierarchies shapes AML over time

https://www.clinicalgenetics.lu.se/article/sanden-et-al-nature-communications-202011579-0 - 2025-12-27

CXCR4 Signaling Has a CXCL-12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

https://www.clinicalgenetics.lu.se/article/ramakrishnan-r-et-al-cell-reports-2020318-0 - 2025-12-27

Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia. Genes Chromosomes Cancer, in press.(link: https://onlinelibrary.wiley.com/doi/10.1002/gcc.22933)

https://www.clinicalgenetics.lu.se/article/moura-castro-lh-et-al-genes-chromosomes-cancer-press - 2025-12-27

IL4 promotes phagocytosis of murine leukemia cells counteracted by CD47 upregulation. Pablo Peña-Martínez, Ramprasad Ramakrishnan, Carl Högberg, Caroline Jansson, David Gisselsson Nord, and Marcus Järås Haematologica, 2021 (Epub ahead of print)

https://www.clinicalgenetics.lu.se/article/pablo-pena-martinez-et-al-haematologica-2021-epub-ahead-print - 2025-12-27

DEVOLUTION-A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data Natalie Andersson, Subhayan Chattopadhyay, Anders Valind, Jenny Karlsson, David Gisselsson 2021 Commun Biol 4(1):1103

https://www.clinicalgenetics.lu.se/article/andersson-n-et-al-commun-biol-411103 - 2025-12-27

Tracing the evolution of aneuploid cancers by multiregional sequencing with CRUST Subhayan Chattopadhyay, Jenny Karlsson, Anders Valind, Natalie Andersson, David Gisselsson 2021 Brief Bioinform bbab292.  doi: 10.1093/bib/bbab292

https://www.clinicalgenetics.lu.se/article/chattopadhyay-et-al-brief-bioinform-bbab292 - 2025-12-27

Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia.Yang M, Vesterlund M, Siavelis I, Moura-Castro LH, Castor A, Fioretos T, Jafari R, Lilljebjörn H, Odom DT, Olsson L, Ravi N, Woodward EL, Harewood L, Lehtiö J, Paulsson K.Nat Commun. 2019 Apr 3;10(1):1519.

https://www.clinicalgenetics.lu.se/article/yang-et-al-nat-commun-2019-apr-31011519 - 2025-12-27

Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells.Chapellier M, Peña-Martínez P, Ramakrishnan R, Eriksson M, Safaee-Talkhoncheh M, Orsmark-Pietras C, Lilljebjörn H, Högberg C, Hagström-Andersson A, Fioretos T, Larsson J, Järås M.Haematologica. 2019 Feb 28. [Epub ahead of print] In press

https://www.clinicalgenetics.lu.se/article/chapellier-et-al-haematologica-2019-feb-28-epub-ahead-print-press - 2025-12-27

 FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis.Hyrenius-Wittsten A, Pilheden M, Falqués-Costa A, Eriksson M, Sturesson H, Schneider P, Wander P, Garcia-Ruiz C, Liu J, Ågerstam H, Hultquist A, Lilljebjörn H, Stam RW, Järås M, Hagström-Andersson AK.Leukemia. 2019 Apr 5. [Epub ahead of print] In press 

https://www.clinicalgenetics.lu.se/article/hyrenius-wittsten-et-al-leukemia-2019-apr-5-epub-ahead-print-press - 2025-12-27

A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells.von Palffy S, Landberg N, Sandén C, Zacharaki D, Shah M, Nakamichi N, Hansen N, Askmyr M, Lilljebjörn H, Rissler M, Karlsson C, Scheding S, Richter J, Eaves CJ, Bhatia R, Järås M, Fioretos T. 

https://www.clinicalgenetics.lu.se/article/von-palffy-et-al-haematologica-2019-oct-3 - 2025-12-27

 Extensive Clonal Branching Shapes the Evolutionary History of High-Risk Pediatric Cancers.Andersson N, Bakker B, Karlsson J, Valind A, Holmquist Mengelbier L, Spierings DCJ, Foijer F, Gisselsson D. 

https://www.clinicalgenetics.lu.se/article/andersson-et-al-cancer-res-2020-apr-18071512-1523 - 2025-12-27

CXCR4 Signaling Has a CXCL-12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

https://www.clinicalgenetics.lu.se/article/ramakrishnan-r-et-al-cell-reports-2020318 - 2025-12-27

Clonal competition within complex evolutionary hierarchies shapes AML over time

https://www.clinicalgenetics.lu.se/article/sanden-et-al-nature-communications-202011579 - 2025-12-27

13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking.

https://www.clinicalgenetics.lu.se/article/minjun-y-et-al-blood-press - 2025-12-27

In November 2020, a hybrid form of the annual conference Europaforum Hässleholm was held. The Centre for European Studies participated during the morning panels on the future of the EU in relation to the pandemic and the US elections.  Note: this article was originally published December 22, 2020.   Read more about the panels on our Swedish website.  

https://www.cfe.lu.se/en/article/coronavirus-and-us-elections-europaforum-hassleholm - 2025-12-27

Around the midpoint of August this year, doctoral candidate Alena Minchenia arrived in Belarus to encounter a nation that had erupted into mass demonstrations. The internationally disputed August 9 presidential elections in Belarus were followed by three days of massive protests countered by extreme state repression in what Minchenia says has since become known as ‘the war’. Since then, the countr

https://www.cfe.lu.se/en/article/adaptive-and-creative-protests-belarus - 2025-12-27

As part of the university's Future Week, LU Futura and the Centre for European Studies organised a seminar on the state of the EU after the pandemic. The four panelists focused on the EU:s prominent history of crises, with the coronavirus as the latest example. Note: this article was originally published on October 21, 2020.   Read about the seminar on our Swedish website.

https://www.cfe.lu.se/en/article/state-union-after-coronavirus - 2025-12-27

The concepts of consultation and participation are often prevalent in the messaging of Swedish ministers on Sweden's presence in the EU. The message is that society, in broad terms, should be able to participate and voice its opinions on Sweden's approach to the EU. But how active is the government in speaking with organisations, groups and businesses when new issues take form in the EU? Not very

https://www.cfe.lu.se/en/article/does-swedish-government-consult-interest-groups-eu-issues - 2025-12-27

The Centre for European Studies at Lund University (CFE) announces the availability of grants for preparing research applications. The Centre has allocated 300.000 SEK (plus LKP) for this purpose during 2021 which will be divided into two calls (spring and autumn). This is the first call. The grant is expected to be used during HT 2021 – VT 2022. Note: this call was originally published March 10,

https://www.cfe.lu.se/en/article/grants-preparing-research-applications - 2025-12-27

To researchers at the Faculties for Humanities and Theology, the Faculty of Social Sciences, the Faculty of Law and the School of Economics and Management. Note: this call was originally published March 10, 2021.  The Centre for European Studies at Lund University announces the availability of funds for seminars, symposia and lectures on European themes during HT 2021 – VT 2022. The theme must hav

https://www.cfe.lu.se/en/article/grants-seminars-symposia-and-lectures-european-themes - 2025-12-27